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Dianne N. Irving, M.A., Ph.D.
International Journal of Sociology and Social Policy 1999, 19:3/4:22-47
Copyright February 1999. Reproduced with
permission.
I. Introduction
The question as to when a human being begins is strictly a scientific question, and should
be answered by human embryologists-not by philosophers, bioethicists, theologians,
politicians, x-ray technicians, movie stars, or obstetricians and gynecologists. The
question as to when a human person begins is a philosophical question. Current discussions
on abortion, human embryo research (including cloning, stem cell research, and the
formation of mixed-species chimeras), and the use of abortifacients involve specific
claims as to when the life of every human being begins. If the "science" used to
ground these various discussions is incorrect, then any conclusions will be rendered
groundless and invalid. The purpose of this article is to focus primarily on a sampling of
the "scientific" myths, and on the objective scientific facts that ought to
ground these discussions. At least it will clarify what the actual international consensus
of human embryologists is with regard to this relatively simple scientific question. In
the final section, I will also address some "scientific" myths that have caused
much confusion within the philosophical discussions on "personhood."
II. When does a human being begin?
Getting a handle on just a few basic human embryological terms accurately can
considerably clarify the drastic difference between the "scientific" myths that
are currently circulating, and the actual objective scientific facts. This would include
such basic terms as: "gametogenesis," "oogenesis,"
"spermatogenesis," "fertilization," "zygote,"
"embryo," and "blastocyst." Only brief scientific descriptions will be
given here for these terms. Further, more complicated, details can be obtained by
investigating any well-established human embryology textbook in the library, such as some
of those referenced below. Please note that the scientific facts presented here are not
simply a matter of my own opinion. They are direct quotes and references from some of the
most highly respected human embryology textbooks, and represent a consensus of human
embryologists internationally.
A. Basic human embryological facts
To begin with, scientifically something very radical occurs between the processes of
gametogenesis and fertilization-the change from a simple part of one human being (i.e., a
sperm) and a simple part of another human being (i.e., an oocyte-usually referred to as an
"ovum" or "egg"), which simply possess "human life", to a
new, genetically unique, newly existing, individual, whole living human being (an
embryonic single-cell human zygote). That is, upon fertilization, parts of human beings
have actually been transformed into something very different from what they were before;
they have been changed into a single, whole human being.
During the process of fertilization, the sperm and the oocyte cease to exist as such, and
a new human being is produced. To understand this, it should be remembered that each
kind of living organism has a specific number and quality of chromosomes that are
characteristic for each member of a species. (The number can vary only slightly if the
organism is to survive.) For example, the characteristic number of chromosomes for a
member of the human species is 46 (plus or minus, e.g., in human beings with Down's or
Turner's syndromes). Every somatic (or, body) cell in a human being has this
characteristic number of chromosomes. Even the early germ cells contain 46
chromosomes; it is only their mature forms - the sex gametes, or sperms and oocytes
- which will later contain only 23 chromosomes each.1
Sperms and oocytes are derived from primitive germ cells in the developing fetus by means of the process known as
"gametogenesis." Because each germ cell normally has 46 chromosomes, the process
of "fertilization" can not take place until the total number of chromosomes in
each are cut in half. This is necessary so that after their fusion at fertilization the
characteristic number of chromosomes in a single individual member of the human species
(46) can be maintained-otherwise we would end up with a monster of some sort.
To accurately see why a sperm or an oocyte are considered as only possessing human life,
and not as living human beings themselves, one needs to look at the basic scientific facts
involved in the processes of gametogenesis and of fertilization. It may help to keep in
mind that the products of gametogenesis and fertilization are very different. The products
of gametogenesis are mature sex gametes with only 23 instead of 46 chromosomes. The
product of fertilization is a living human being with 46 chromosomes. Gametogenesis refers
to the maturation of germ cells, resulting in gametes. Fertilization refers to the
initiation of a new human being.
1) Gametogenesis
As the human embryologist Larsen2 states it, gametogenesis is the process that converts
primordial germ cells (primitive sex cells) into mature sex gametes-in the male
(spermatozoa, or sperms), and in the female (definitive oocytes). The timing of
gametogenesis is different in males and in females. The later stages of spermatogenesis in
males occur at puberty, and continue throughout adult life. The process involves the
production of spermatogonia from the primitive germ cells, which in turn become primary
spermatocytes, and finally spermatids-or mature spermatozoa (sperms). These mature sperms
will have only half of the number of their original chromosomes-i.e., the number of
chromosomes has been cut from 46 to 23, and therefore they are ready to take part in
fertilization.3
Oogenesis begins in the female during fetal life. The total number of primary
oocytes-about 7 million-is produced in the female fetus' ovaries by 5 months of gestation
in the mother's uterus. By birth, only about 700,000 - 2 million remain. By puberty, only
about 400,000 remain. The process includes several stages of maturation-the production of
oogonia from primitive germ cells, which in turn become primary oocytes, which become
definitive oocytes only at puberty. This definitive oocyte is what is released each month
during the female's menstrual period, but it still has 46 chromosomes. In fact, it does
not reduce its number of chromosomes until and unless it is fertilized by the sperm,
during which process the definitive oocyte becomes a secondary oocyte with only 23
chromosomes. 4
This halving of the number of chromosomes in the oocytes takes place by the process known
as meiosis. Many people confuse meiosis with a different process known as mitosis, but
there is an important difference. Mitosis refers to the normal division of a somatic or of
a germ cell in order to increase the number of those cells during growth and development.
The resulting cells contain the same number of chromosomes as the previous cells-in human
beings, 46. Meiosis refers to the halving of the number of chromosomes that are normally
present in a germ cell - the precursor of a sperm or a definitive oocyte - in order for
fertilization to take place. The resulting gamete cells have only half of the number of
chromosomes as the previous cells-in human beings, 23.
One of the best and most technically accurate explanations for this critical process of
gametogenesis is by Ronan O'Rahilly,5
the human embryologist who developed the classic
Carnegie stages of human embryological development. He also sits on the international
board of Nomina Embryologica (which determines the correct terminology to be used in human
embryology textbooks internationally):
"Gametogenesis is the production of [gametes], i.e., spermatozoa and oocytes. These
cells are produced in the gonads, i.e., the testes and ovaries respectively. ... During
the differentiation of gametes, diploid cells (those with a double set of chromosomes, as
found in somatic cells [46 chromosomes])
are termed primary, and haploid cells (those with a single set of chromosomes [23
chromosomes]) are called secondary. The reduction of chromosomal number ... from 46 (the
diploid number or 2n) to 23 (the haploid number or n) is accomplished by a cellular
division termed meiosis. ... Spermatogenesis, the production of spermatozoa, continues
from immediately after puberty until old age. It takes place in the testis, which is also
an endocrine gland, the interstitial cells of which secrete testosterone. Previous to
puberty, spermatogonia in the simiferous tubules of the testis remain relatively inactive.
After puberty, under stimulation from the interstitial cells, spermatogonia proliferate
... and some become primary spermatocytes. When these undergo their first maturation
division (meiosis 1), they become secondary spermatocytes. The second maturation division
(meiosis 2) results in spermatids, which become converted into
spermatozoa."6
"Oogenesis is the production and maturation of oocytes, i.e.; the female gametes
derived from oogonia. Oogonia (derived from primordial germ cells) multiply by mitosis and
become primary oocytes. The number of oogonia increases to nearly seven million by the
middle of prenatal life, after which it diminishes to about two million at birth. From
these, several thousand oocytes are derived, several hundred of which mature and are
liberated (ovulated) during a reproductive period of some thirty years. Prophase of
meiosis 1 begins during fetal life but ceases at the diplotene state, which persists
during childhood. ... After puberty, meiosis 1 is resumed and a secondary oocyte ... is
formed, together with polar body 1, which can be regarded as an oocyte having a reduced
share of cytoplasm. The secondary oocyte is a female gamete in which the first meiotic
division is completed and the second has begun. From oogonium to secondary oocyte takes
from about 12 to 50 years to be completed. Meiosis 2 is terminated after rupture of the
follicle (ovulation) but only if a spermatozoon penetrates. ... The term 'ovum' implies
that polar body 2 has been given off, which event is usually delayed until the oocyte has
been penetrated by a spermatozoon (i.e., has been fertilized). Hence a human ovum does not
[really] exist. Moreover the term has been used for such disparate structures as an oocyte
and a three-week embryo, and therefore should be discarded, as a fortiori should
'egg'."7 (Emphasis added.)
Thus, for fertilization to be accomplished, a mature sperm and a mature human oocyte are
needed. Before fertilization,8 each has only 23 chromosomes. They each possess "human
life," since they are parts of a living human being; but they are not each whole
living human beings themselves. They each have only 23 chromosomes, not 46 chromosomes-the
number of chromosomes necessary and characteristic for a single individual member of the
human species. Furthermore, a sperm can produce only "sperm" proteins and
enzymes; an oocyte can produce only "oocyte" proteins and enzymes; neither alone
is or can produce a human being with 46 chromosomes.
Also, note O'Rahilly's statement that the use of terms such as "ovum" and
"egg"-which would include the term "fertilized egg"-is scientifically
incorrect, has no objective correlate in reality, and is therefore very
misleading-especially in these present discussions. Thus these terms themselves would
qualify as "scientific" myths. The commonly used term, "fertilized
egg," is especially very misleading, since there is really no longer an egg (or
oocyte) once fertilization has begun. What is being called a "fertilized egg" is
not an egg of any sort; it is a human being.
2) Fertilization
Now that we have looked at the formation of the mature haploid sex gametes, the next
important process to consider is fertilization. O'Rahilly defines fertilization as:
"... the procession of events
that begins when a spermatozoon makes contact with a secondary oocyte or its investments,
and ends with the intermingling of maternal and paternal chromosomes at metaphase of the
first mitotic division of the zygote. The zygote is characteristic of the last phase of
fertilization and is identified by the first cleavage spindle. It is a unicellular
embryo."9 (Emphasis added.)
The fusion of the sperm (with 23 chromosomes) and the oocyte (with 23 chromosomes) at
fertilization results in a live human being, a single-cell human zygote, with 46
chromosomes-the number of chromosomes characteristic of an individual member of the human
species. Quoting Moore:
"Zygote: This cell results from the union of an oocyte and a sperm. A zygote is the
beginning of a new human being (i.e., an embryo). The expression fertilized ovum refers to
a secondary oocyte that is impregnated by a sperm; when fertilization is complete, the
oocyte becomes a zygote."10 (Emphasis added.)
This new single-cell human being immediately produces specifically human proteins and
enzymes11 (not carrot or frog enzymes and proteins), and genetically directs his/her own
growth and development. (In fact, this genetic growth and development has been proven not
to be directed by the mother.)12
Finally, this new human being-the single-cell human zygote-is biologically an individual,
a living organism-an individual member of the human species. Quoting Larsen:
"... [W]e begin our description of the developing human with the formation and
differentiation of the male and female sex cells or gametes, which will unite at
fertilization to initiate the embryonic development of a new individual."13
(Emphasis added.)
In sum, a human sperm and a human oocyte are products of gametogenesis-each has only 23
chromosomes. They each have only half of the required number of chromosomes for a human
being. They cannot singly develop further into human beings. They produce only
"gamete" proteins and enzymes. They do not direct their own growth and
development. And they are not individuals, i.e., members of the human species. They are
only parts-each one a part of a human being.
On the other hand, a human being is the immediate product of fertilization. As such he/she
is a single-cell embryonic zygote, an organism with 46 chromosomes, the number required of
a member of the human species. This human being immediately produces specifically human
proteins and enzymes, directs his/her own further growth and development as human, and is
a new, genetically unique, newly existing, live human individual.
After fertilization the single-cell human embryo doesn't become another kind of thing. It
simply divides and grows bigger and bigger, developing through several stages as an embryo
over an 8-week period. Several of these developmental stages of the growing embryo are
given special names, e.g., a morula (about 4 days), a blastocyst (5-7 days), a bilaminar
(two layer) embryo (during the second week), and a trilaminar (3-layer) embryo (during the
third week).14
B. "Scientific" myths and scientific fact:
Given these basic facts of human embryology, it is easier to recognize the many
scientifically inaccurate claims that have been advanced in the discussions about
abortion, human embryo research, cloning, stem cell research, the formation of chimeras,
and the use of abortifacients -and
why these discussions obfuscate the objective scientific facts. The following is just a
sampling of these current "scientific" myths.
Myth 1: "Prolifers claim that the
abortion of a human embryo or a human fetus is wrong because it destroys human life. But
human sperms and human ova are human life, too. So prolifers would also have to agree that
the destruction of human sperms and human ova are no different from abortions-and that is
ridiculous!"
Fact 1: As pointed out above in the background section, there is a radical
difference, scientifically, between parts of a human being that only possess "human
life" and a human embryo or human fetus that is an actual "human being."
Abortion is the destruction of a human being. Destroying a human sperm or a human oocyte
would not constitute abortion, since neither are human beings. The issue is not when does
human life begin, but rather when does the life of every human being begin. A human kidney
or liver, a human skin cell, a sperm or an oocyte all possess human life, but they are not
human beings-they are only parts of a human being. If a single sperm or a single oocyte
were implanted into a woman's uterus, they would not grow; they would simply disintegrate.
Myth 2: "The product of fertilization is simply a 'blob,' a 'bunch of cells',
a 'piece of the mother's tissues'."
Fact 2: As demonstrated above, the human embryonic organism formed at fertilization
is a whole human being, and therefore it is not just a "blob" or a "bunch
of cells." This new human individual also has a mixture of both the mother's and the
father's chromosomes, and therefore it is not just a "piece of the mother's
tissues". Quoting Carlson:
"... [T]hrough the mingling of maternal and paternal chromosomes, the zygote is a
genetically unique product of chromosomal reassortment, which is important for the
viability of any species."15(Emphasis
added.)
Myth 3: "The immediate product of fertilization is just a 'potential' or a
'possible' human being-not a real existing human being."
Fact 3: As demonstrated above, scientifically there is absolutely no question
whatsoever that the immediate product of fertilization is a newly existing human being. A
human zygote is a human being. It is not a "potential" or a "possible"
human being. It's an actual human being-with the potential to grow bigger and develop its
capacities.
Myth 4: "A single-cell human zygote, or embryo, or fetus are not human beings,
because they do not look like human beings."
Fact 4: As all human embryologists know, a single-cell human zygote, or a more
developed human embryo, or human fetus is a human being-and that that's the way they are
supposed to look at those particular periods of development.
Myth 5: "The immediate product of fertilization is just an 'it'-it is neither
a girl nor a boy."
Fact 5: The immediate product of fertilization is genetically already a girl or a
boy-determined by the kind of sperm that fertilizes the oocyte. Quoting Carlson again:
"...[T]he sex of the future embryo is determined by the chromosomal complement of the
spermatozoon. (If the sperm contains 22 autosomes and 2 X chromosomes, the embryo will be
a genetic female, and if it contains 22 autosomes and an X and a Y chromosome, the embryo
will be a genetic male.)"16
Myth 6: "The embryo and the embryonic period begin at implantation."
(Alternative myths claim 14 days, or 3 weeks.)
Fact
6: These are a few of the most common myths perpetuated sometimes even within
quasi-scientific articles-especially within the bioethics literature. As demonstrated
above, the human embryo, who is a human being, begins at fertilization-not at implantation
(about 5-7 days), 14-days, or 3 weeks. Thus the embryonic period also begins at
fertilization, and ends by the end of the eighth week, when the fetal period begins.
Quoting O'Rahilly:
"Prenatal life is conveniently divided into two phases: the embryonic and the fetal.
The embryonic period proper during which the vast majority of the named structures of the
body appear, occupies the first 8 postovulatory weeks. ... [T]he fetal period extends from
8 weeks to birth ..."17 (Emphasis added.)
Myth 7: "The product of fertilization, up to 14-days, is not an embryo; it is
just a 'pre-embryo'-and therefore it can be used in experimental research, aborted, or
donated."
Fact 7: This "scientific" myth is perhaps the most common error, which
pervades the current literature. The term "pre-embryo" has quite a long and
interesting history. (See Irving and Kischer, The Human Development Hoax: Time To Tell The
Truth!, for extensive details and references.) But it roughly goes back to at least 1979
in the bioethics writings of Jesuit theologian Richard McCormick in his work with the
Ethics Advisory Board to the United States Department of Health, Education and
Welfare,18
and those of frog developmental biologist Dr. Clifford Grobstein in a 1979 article in
Scientific American,19 and most notably in his classic book,
Science and the Unborn:
Choosing Human Futures (1988).20
Both McCormick and Grobstein subsequently continued propagating this scientific myth as
members of the Ethics Committee of the American Fertility Society, and in numerous
influential bioethics articles, leading to its common use in bioethics, theological, and
public policy literature to this day.
The term "pre-embryo" was also used as the rationale for permitting human embryo
research in the British Warnock Committee Report (1984),21 and then picked up by
literally hundreds of writers internationally, including, e.g., Australian writers Michael
Lockwood, Michael Tooley, Alan Trounson-and especially by Peter Singer (a philosopher),
Pascal Kasimba (a lawyer), Helga Kuhse (an ethicist), Stephen Buckle (a philosopher) and
Karen Dawson (a geneticist, not a human embryologist).
Note that none of these is even a scientist, with the exception of Karen Dawson, who is
just a geneticist.
Oddly, the influential book by Singer, Kuhse, Buckle, and Dawson, Embryo
Experimentation,22
(which uses the term "pre-embryo," and which contains no
scientific references for its "human embryology" chart or its list of
"scientific" terms), along with the work of theologian McCormick and frog
developmental biologist Grobstein, was used in the United States as the scientific basis
for the 1994 National Institutes of Heath (NIH) Human Embryo Research Report.23
That
Report concluded that the "preimplantation embryo" (they, too, originally used
the term "pre-embryo") had only a "reduced moral status." (Both the
Warnock Report and the NIH Report admitted that the 14-day limit for human embryo research
was arbitrary, and could and must be changed if necessary.)
It is particularly in the writings of these and other bioethicists that so much incorrect
science is claimed in order to "scientifically" ground the
"pre-embryo" myth and therefore "scientifically" justify many of the
issues noted at the beginning of this article. This would include abortion, as well as the
use of donated or "made-for-research" early human embryos in destructive
experimental human embryo research (such as infertility research, cloning, stem cell
research, the formation of chimeras, etc.). To begin with, it has been demonstrated above that the immediate product of
fertilization is a human being with 46 chromosomes, a human embryo, an individual member
of the human species, and that this is the beginning of the embryonic period. However,
McCormick and Grobstein24 claim that even though the product of fertilization is
genetically human, it is not a "developmental individual" yet-and in turn, this
"scientific fact" grounds their moral claim about this "pre-embryo."
Quoting McCormick:
"I contend in this paper that the moral status-and specifically the controversial
issue of personhood-is related to the attainment of developmental individuality (being the
source of one individual) ... It should be noted that at the zygote stage the genetic
individual is not yet developmentally single-a source of only one individual. As we will
see, that does not occur until a single body axis has begun to form near the end of the
second week post fertilization when implantation is underway."25 (Emphasis added.)
Sounds very scientific. However, McCormick's embryology is already self-contradictory.
Implantation takes place at 5-7 days. The "single body axis" to which he refers
is the formation of the primitive streak, which takes place at 14 days. McCormick often
confuses these different periods in his writings. But McCormick continues:
"This multicellular entity, called a blastocyst, has an outer cellular wall, a
central fluid-filled cavity and a small gathering of cells at one end known as the inner
cell mass. Developmental studies show that the cells of the outer wall become the
trophoblast (feeding layer) and are precursors to the later placenta. Ultimately, all
these cells are discarded at birth."26Emphasis added.)
The clear implication is that there is absolutely no relationship or interaction between
these two cell layers, and so the "entity" is not a "developmental
individual" yet. However, quoting Larsen:
"These centrally placed blastomeres are now called the inner cell mass, while the
blastomeres at the periphery constitute the outer cell mass. Some exchange occurs between
these groups. ... The cells of this germ disc (the inner cell layer) develop into the
embryo proper and also contribute to some of the extraembryonic membranes."27
(Emphasis added.)
Similarly, it is not factually correct to state that all of the cells from the outer
trophoblast layer are discarded after birth. Quoting Moore:
"The chorion, the amnion, the yolk sac, and the allantois constitute the fetal
membranes. They develop from the zygote but do not participate in the formation of the
embryo or fetus-except for parts of the yolk sac and allantois. Part of the yolk sac is
incorporated into the embryo as the primordium of the gut. The allantois forms a fibrous
cord that is known as the urachus in the fetus and the median umbilical ligament in the
adult. It extends from the apex of the urinary bladder to the umbilicus."28
(Emphasis added.)
Since scientists, in trying to "reach" young students in a more familiar
language, sometimes use popularized (but scientifically inaccurate and misleading) terms
themselves, the ever-vigilant O'Rahilly expresses concern in his classic text about the
use of the term "fetal membranes":
"The developmental adnexa, commonly but inaccurately referred to as the 'fetal
membranes,' include the trophoblast, amnion, chorion, umbilical vesicle (yolk sac),
allantoic diverticulum, placenta and umbilical cord. They are genetically a part of the
individual and are composed of the same germ layers."29
(Emphasis added.)
Consequently, it is also scientifically incorrect to claim that only the inner cell layer
constitutes the "embryo proper." The entire blastocyst-including both the inner
and the outer cell layers-is the human embryo, the human being, the human individual.
Finally, McCormick claims that this "pre-embryo" has not yet decided how many
individuals it will become, since the cells are totipotent and twinning can still take
place. Therefore, they argue, there is no "individual" present until 14-days and
the formation of the primitive streak, after which twinning cannot take place.30
However, twinning is possible after 14 days, e.g., with fetus-in-fetu and Siamese twins.
Quoting from O'Rahilly again:
"Partial duplication at an early stage and attempted duplication from 2 weeks onward
(when bilateral symmetry has become manifest) would result in conjoined twins (e.g.,
'Siamese twins')."31 (Emphasis added.)
And even Karen Dawson acknowledges this as scientific fact in her article in Embryo
Experimentation:
"After the time of primitive streak formation, other events are possible which
indicate that the notion of 'irreversible individuality' may need some review if it is to
be considered as an important criterion in human life coming to be the individual human
being it is ever thereafter to be. There are two conditions which raise questions about
the adequacy of this notion: conjoined twins, sometimes known as Siamese twins, and
fetus-in-fetu. ... Conjoined twins arise from the twinning process occurring after the
primitive streak has begun to form, that is, beyond 14 days after fertilization, or, in
terms of the argument from segmentation, beyond the time at which irreversible
individuality is said to exist. ... This situation weakens the possibility of seeing
individuality as something irreversibly resolved by about 14 days after fertilization.
This in turn raises questions about the adequacy of using the landmark of segmentation in
development as the determinant of moral status."32
(Emphasis added.)
It is unfortunate that the NIH Human Embryo Research
Panel
33 did not read this particular
portion of the Singer et al. book before making their recommendations about the moral
status of the early human embryo.
The scientific fact is that there is no such thing as a "pre-embryo" in the real
world. The term is a complete myth. It was fabricated out of thin air in order to justify
a number of things that ordinarily would not be justifiable. Quoting O'Rahilly, who sits
on the international board of Nomina Embryologica, again:
"The ill-defined and inaccurate term 'pre-embryo,' which includes the embryonic disk,
is said either to end with the appearance of the primitive streak or to include
neurulation. The term is not used in this book."34 (Emphasis added.)
Unfortunately, the convenient but mythological term "pre-embryo" will be used to
"scientifically" justify several of the other "scientific" myths to
follow, which in turn will be used to justify public policy on abortion and human embryo
research world-wide.
Myth 8: "Pregnancy begins with the
implantation of the blastocyst (i.e., about 5-7 days)."
Fact 8: This definition of "pregnancy" was initiated to accommodate the
introduction of the process of in vitro fertilization, where fertilization takes place
artificially outside the mother in a petri dish, and then the embryo is artificially
introduced into the woman's uterus so that implantation of the embryo can take place.
Obviously, if the embryo is not within the woman's body, she is not "pregnant"
in the literal, traditional sense of the term. However, this artificial situation cannot
validly be substituted back to redefine "normal pregnancy," in which
fertilization does take place within the woman's body in her fallopian tube, and
subsequently the embryo itself moves along the tube to implant itself into her uterus. In
normal situations, pregnancy begins at fertilization, not at implantation. Quoting
Carlson:
"Human pregnancy begins with the fusion of an egg and a sperm, but a great deal of
preparation precedes this event. First both male and female sex cells must pass through a
long series of changes (gametogenesis) that converts them genetically and phenotypically
into mature gametes, which are capable of participating in the process of fertilization.
Next, the gametes must be released from the gonads and make their way to the upper part of
the uterine tube, where fertilization normally takes place. Finally, the fertilized egg,
now properly called an embryo, must make its way into the uterus, where it sinks into the
uterine lining (implantation) to be nourished by the mother."35 (Emphasis added.)
Myth 9: "The 'morning-after pill,' RU486, and the IUD are not abortifacient;
they are only methods of contraception."
Fact 9: The "morning-after pill," RU486, and the IUD can be
abortifacient, if fertilization has taken place. Then they would act to prevent the
implantation of an already existing human embryo-the blastocyst-which is an existing human
being. If the developing human blastocyst is prevented from implanting into the uterus,
then obviously the embryo dies. In effect, these chemical and mechanical methods of
contraception have become methods of abortion as well. Quoting Moore:
"The administration of relatively large doses of estrogens ('morning-after pill') for
several days, beginning shortly after unprotected sexual intercourse, usually does not
prevent fertilization but often prevents implantation of the blastocyst.
Diethylstilbestrol, given daily in high dosage for 5-6 days, may also accelerate passage
of the dividing zygote along the uterine tube ... Normally, the endometrium progresses to
the secretory phase of the menstrual cycle as the zygote forms, undergoes cleavage, and
enters the uterus. The large amount of estrogen disturbs the normal balance between
estrogen and progesterone that is necessary for preparation of the endometrium for
implantation of the blastocyst. Postconception administration of hormones to prevent
implantation of the blastocyst is sometimes used in cases of sexual assault or leakage of
a condom, but this treatment is contraindicated for routine contraceptive use. The
'abortion pill' RU486 also destroys the conceptus by interrupting implantation because of
interference with the hormonal environment of the implanting embryo. ... An intrauterine
device (IUD) inserted into the uterus through the vagina and cervix usually interferes
with implantation by causing a local inflammatory reaction. Some IUDs contain progesterone
that is slowly released and interferes with the development of the endometrium so that
implantation does not usually occur."36 (Emphasis added.)
And since the whole human blastocyst is the embryonic human being-not just the inner cell layer-the use of chemical abortifacients that
act "only" on the outer trophoblast layer of the blastocyst, e.g.,
methotrexate,37 would be abortifacient as well.
Myth 10: "Human embryo research, human
cloning, stem cell research, and the formation of chimeras are acceptable kinds of
research because until implantation or 14 days there is only a 'pre-embryo', a 'potential'
human embryo or human being present. A real human embryo and a human being (child) do not
actually begin unless and until the 'pre-embryo' is implanted into the mother's
uterus."
Fact 10: These claims are currently being made by bioethicists, research
scientists, pharmaceutical companies, and other biotech research companies-even by some
members of Congress. However, they too are "scientific" myths.
Scientifically it is perfectly clear that there is no such thing as a
"pre-embryo," as demonstrated in Fact 7. As demonstrated in the background
material, the immediate product of fertilization is a human being, a human embryo, a human
child-the zygote. This zygote is a newly existing, genetically unique, genetically male or
female, individual human being-it is not a "potential" or a "possible"
human being. And this developing human being is a human being, a human embryo, a human
child whether or not it is implanted artificially into the womb of the mother.
Fertilization and cloning are different processes, but the immediate products of these
processes are the same. The immediate product of human cloning would also be a human
being-just as in human fertilization. It is not a "pre-embryo" or a
"potential" human embryo or human being. Stem cell research obtains its
"stem cells" by essentially exploding or otherwise destroying and killing a
newly existing human blastocyst who is, scientifically, an existing human being.
The formation of chimeras, i.e., the fertilization of a gamete of one species (e.g., a
human oocyte) with the gamete of another species (e.g., a monkey sperm) also results in an
embryo that is "half-human." All of these types of research have been banned by
most countries in the world. And all of these types of research are essentially human
embryo research-for which the use of federal funds has been banned.
Myth 11: "Certain early stages of the developing human embryo and fetus, e.g.,
during the formation of ancestral fish gills or tails, demonstrates that it is not yet a
human being, but is only in the process of becoming one. It is simply 'recapitulating' the
historical evolution of all of the species."
Fact 11: This "scientific" myth is yet another version of the
"potential," "possible," "pre-embryo" myths. It is an
attempt to deny the early human embryo its real identity as a human being and its real
existence. But quoting once again from O'Rahilly:
"The theory that successive stages of individual development (ontogeny) correspond
with ('recapitulate') successive adult ancestors in the line of evolutionary descent
(phylogeny) became popular in the 19th century as the so-called biogenetic law. This
theory of recapitulation, however, has had a 'regrettable influence in the progress of
embryology' (citing de Beer). ... Furthermore, during its development an animal departs
more and more from the form of other animals. Indeed, the early stages in the development
of an animal are not like the adult stages of other forms, but resemble only the early
stages of those animals."
38
Hence, the developing human embryo or fetus is not a "fish" or a
"frog," but is categorically a human being-as has been already demonstrated.
III. When does a human person begin?
The question as to when a human person begins
is a philosophical question-not a scientific question. I will not go into great detail
here,39 but "personhood" begins when the human being begins-at fertilization.
But since many of the current popular "personhood" claims in bioethics are also
based on mythological science, it would be useful to just look very briefly at these
philosophical (or sometimes, theological) arguments simply for scientific accuracy as
well.
Philosophically, virtually any claim for so-called "delayed personhood"-that is,
"personhood" does not start until some point after fertilization-involves the
theoretical disaster of accepting that the idea or concept of a mind/body split has any
correlate or reflects the real world. Historically this problem was simply the consequence
of wrong-headed thinking about reality, and was/is totally indefensible. It was abandoned
with great embarrassment after Plato's time (even by Plato himself in his Parmenides!),
but unfortunately resurfaces from time to time, e.g., as with Descartes in his
Meditations, and now again with contemporary bioethics.
40 And as in the question of when
a human being begins, if the science used to ground these philosophical
"personhood" arguments is incorrect, the conclusions of these arguments (which
are based on that incorrect science) are also incorrect and invalid.
Myth 12: "Maybe a human being begins at fertilization, but a human person does
not begin until after 14-days, when twinning cannot take place."
Fact 12: The particular argument in Myth 12 is also made by McCormick and Grobstein
(and their numerous followers). It is based on their biological claim that the
"pre-embryo" is not a developmental individual, and therefore not a person,
until after 14 days when twinning can no longer take place. However, it has already been
scientifically demonstrated here that there is no such thing as a "pre-embryo,"
and that in fact the embryo begins as a "developmental individual" at
fertilization. Furthermore, twinning can take place after 14 days. Thus simply on the
level of science, the philosophical claim of "personhood" advanced by these
bioethicists is invalid and indefensible.
Myth 13: "A human person begins with 'brain birth,' the formation of the
primitive nerve net, or the formation of the cortex-all physiological structures necessary
to support thinking and feeling."
Fact 13: Such claims are all pure mental speculation, the product of imposing
philosophical (or theological) concepts on the scientific data, and have no scientific
evidence to back them up. As the well-known neurological researcher D. Gareth Jones has
succinctly put it, the parallelism between "brain death" and "brain
birth" is scientifically invalid. "Brain death" is the gradual or rapid
cessation of the functions of a brain. "Brain birth" is the very gradual
acquisition of the functions of a developing neural system. This developing neural system
is not a brain. He questions, in fact, the entire assumption and asks what neurological
reasons there might be for concluding that an incapacity for consciousness becomes a
capacity for consciousness once this point is passed. Jones continues that the alleged
symmetry is not as strong as is sometimes assumed, and that it has yet to be provided with
a firm biological base.41
Myth 14: "A 'person' is defined in terms of the active exercising of 'rational
attributes' (e.g., thinking, willing, choosing, self-consciousness, relating to the world
around one, etc.), and/or the active exercising of 'sentience' (e.g., the feeling of pain
and pleasure)."
Fact 14: Again, these are philosophical terms or concepts, which have been
illegitimately imposed on the scientific data. The scientific fact is that the brain,
which is supposed to be the physiological support for both "rational attributes"
and "sentience," is not actually completely developed until young adulthood.
Quoting Moore:
"Although it is customary to
divide human development into prenatal (before birth) and postnatal (after birth) periods,
birth is merely a dramatic event during development resulting in a change in environment.
Development does not stop at birth. Important changes, in addition to growth, occur after
birth (e.g., development of teeth and female breasts). The brain triples in weight between
birth and 16 years; most developmental changes are completed by the age of
25."42
(Emphasis added.)
One should also consider simply the logical-and very real-consequences if a
"person" is defined only in terms of the actual exercising of "rational
attributes" or of "sentience." What would this mean for the following list
of adult human beings with diminished "rational attributes": e.g., the mentally
ill, the mentally retarded, the depressed elderly, Alzheimer's and Parkinson's patients,
drug addicts, alcoholics-and for those with diminished "sentience," e.g., the
comatose, patients in a "vegetative state," paraplegics, and other paralyzed and
disabled patients, diabetics or other patients with nerve or brain damage, etc.? Would
they then be considered as only human beings but not also as human persons? Would that
mean that they would not have the same ethical and legal rights and protections as those
adult human beings who are considered as persons? Is there really such a "split"
between a human being and a human person?
In fact, this is the position of bioethics writers such as the Australian animal rights
philosopher Peter Singer,[43] the recently appointed Director of the Center for Human
Values at Princeton University. Singer argues that the higher primates, e.g., dogs, pigs,
apes, monkeys, are persons-but that some human beings, e.g., even normal human infants,
and disabled human adults, are not persons. Fellow bioethicist Norman Fost actually
considers "cognitively impaired" adult human beings as "brain dead."
Philosopher/bioethicist R.G. Frey has also published that many of the adult human beings
on the above list are not "persons," and suggests that they be substituted for
the higher primates who are "persons" in purely destructive experimental
research.44 The list goes on.
IV. Conclusions
Ideas do have concrete consequences-not only in one's personal life, but also in the
formulation of public policies. And once a definition is accepted in one public policy,
the logical extensions of it can then be applied, invalidly, in many other policies, even
if they are not dealing with the same exact issue-as happens frequently in bioethics.
Thus, the definitions of "human being" and of "person" that have been
concretized in the abortion debates have been transferred to several other areas, e.g.,
human embryo research, cloning, stem cell research, the formation of chimeras, the use of
abortifacients-even to the issues of brain death, brain birth, organ transplantation, the
removal of food and hydration, and research with the mentally ill or the disabled. But
both private choices and public policies should incorporate sound and accurate science
whenever possible. What I have tried to indicate is that in these current discussions,
individual choices and public policies have been based on "scientific" myth,
rather than on objective scientific facts.
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